Trial Details

Trial status:

In follow-up (non-recruiting)

Recruitment start date:

30/12/2010

Funder:

University College London

Sponsor:

UCL

Chief Investigator:

Prof Adele Fielding

Recruitment target:

811

EudraCT number:

2009-012717-22

Contact details:

ctc.ukall14@ucl.ac.uk

Note: For enquiries only. DO NOT use for clinical referrals.

UKALL14

A randomised trial for adults with newly diagnosed acute lymphoblastic leukaemia

Description

Design: UKALL14 is a Phase III multicentre randomised trial for adults with newly-diagnosed Acute Lymphoblastic Leukaemia (ALL). The main randomisations investigate standard induction chemotherapy with or without Rituximab (for B-cell ALL) or Nelarabine (for T-cell ALL).

Treatment: Initially, eligible patients will have two phases of induction chemotherapy. Patients with Philadelphia negative ALL will receive pegylated asparaginase as part of their induction. 50% of B-cell ALL patients will receive Rituximab weekly for 4 weeks during phase 1 induction. 50% of T-cell ALL patients will receive three doses of Nelarabine after phase 2 induction.

After induction, patients with a matched sibling donor will receive a stem cell transplant, either myeloablative if aged ≤40 or non-myeloablative if aged ≥41. Patients with no sibling donor will be assigned further treatment depending on their relapse risk. Patients with ‘high risk’ disease and who have a suitable unrelated donor will have a stem cell transplant. Patients who are ‘standard risk’, or who do not have a suitable donor will continue with intensification, consolidation and maintenance chemotherapy.

Philadelphia positive patients will also receive Imatinib throughout treatment.

Patients will be followed up for at least 2 years post-treatment.

Patients will have regular minimal residual disease testing throughout treatment.

Key inclusion/exclusion criteria: Patients must be aged 25-65 years old (19-65 if Philadelphia positive) with newly-diagnosed, previously untreated ALL. Patients cannot have known HIV infection, a history of hepatitis B or C infection, blast transformation of CML, mature B-cell leukaemia or be pregnant or lactating.

Duration of recruitment: 7.5 years

Aim

The main aims of UKALL14 are to determine: whether Rituximab can improve outcomes for patients with B-cell ALL; whether nelarabine can improve outcomes for patients with T-cell ALL; whether patients can tolerate pegylated asparaginase, and whether they develop anti-asparaginase antibodies; and whether unrelated donor stem cell transplantation can improve outcomes for patients at a high risk of relapse.

The trial also aimed to investigate the optimal scheduling of the anti-mucositis drug palifermin in myeloablative transplant patients, however as the drug is no longer available, this aim will not be fully addressed.

Contact the trial team

View trial documents

Trial protocols

Trial protocols must not be applied to patients treated outside trials. UCL CTC can only ensure that approved trial investigators are provided with amendments to protocols.

Name	Version	Current vers	Release date
Protocol v1	1.0	Historic	11/11/2009
Protocol v11	11.0	Historic	11/09/2017
Protocol v12	12.0	Historic	26/06/2018
Protocol v2	2.0	Historic	17/05/2010
Protocol v3	3.0	Historic	18/08/2010
Protocol v4	4.0	Historic	24/04/2012
Protocol v5	5.0	Historic	20/07/2012
Protocol v6	6.0	Historic	20/06/2014
Protocol v6.1	6.1	Historic	27/01/2015
Protocol v7	7.0	Historic	09/09/2015
Protocol v7 corrected	7.0	Historic	10/12/2015
Protocol v8	8.0	Historic	12/05/2016
Protocol v9	9.0	Historic	17/02/2017

Trial documents

Name	Type	Version	Current vers	Release date
Annual follow up form	CRF	3	Current	20/08/2020
Annual follow up form (relapse and second cancer)	CRF	3	Current	20/08/2020
Consent Form	InformedConsentForm	1.2	Current	29/04/2015
Consent Form - Genetic Testing - Bone Marrow	InformedConsentForm	1.0	Current	09/09/2015
Consent Form - Genetic Testing - Buccal Swab	InformedConsentForm	1.0	Current	09/09/2015
Consent Form - Pregnancy Monitoring - Partners	InformedConsentForm	1.0	Current	01/08/2012
Consent Form - Pregnancy Monitoring - Patient	InformedConsentForm	1.0	Current	01/08/2012
CRF - Adverse Event Consolidation	CRF	3.0	Current	27/11/2015
CRF - Adverse Event Induction Phase 2	CRF	3.0	Current	27/11/2015
CRF - Adverse Event Induction Phase1	CRF	3.0	Current	27/11/2015
CRF - Adverse Event Intensification	CRF	3.0	Current	27/11/2015
CRF - Adverse Event Transplant	CRF	3.0	Current	27/11/2015
CRF - AE of Special Interest	CRF	1.0	Current	27/11/2015
CRF - Annual Follow up (Not in CR)	CRF	2.0	Current	20/04/2015
CRF - Centre Transfer	CRF	3.0	Current	10/03/2016
CRF - Consent Constitutional DNA	CRF	1.0	Current	27/11/2015
CRF - Consolidation Treatment	CRF	2.0	Current	20/04/2015
CRF - Cytogenetics	CRF	3.0	Current	03/05/2013
CRF - Death	CRF	3.0	Current	27/11/2015
CRF - Induction Treatment Phase 1	CRF	3.0	Current	20/04/2015
CRF - Induction Treatment Phase 2	CRF	3.0	Current	20/04/2015
CRF - Intensification Treatment	CRF	2.0	Current	20/04/2015
CRF - Late Effects	CRF	1.0	Current	10/03/2016
CRF - Lost to Follow Up	CRF	3.0	Current	27/11/2015
CRF - Maintenance Treatment	CRF	1.0	Current	08/12/2010
CRF - Post Induction Registration Maintenance	CRF	2.0	Current	20/04/2015
CRF - Post Induction Registration Transplant	CRF	2.0	Current	20/04/2015
CRF - Post Induction Treatment Allocation (PITA)	CRF	2.0	Current	20/04/2015
CRF - Registration	CRF	6.0	Current	27/11/2015
CRF - 'Registration only' Annual Followup v2	CRF	2.0	Current	20/08/2018
CRF - 'Registration only' GvHD Form v2	CRF	2.0	Current	20/08/2018
CRF - 'Registration only' Induction Treatment v2	CRF	2.0	Current	20/08/2018
CRF - 'Registration only' Post-Induction Chemotherapy v2	CRF	2.0	Current	20/08/2018
CRF - 'Registration only' Sub-study Entry v2	CRF	2.0	Current	20/08/2018
CRF - 'Registration only' Transplant to Day100 v2	CRF	2.0	Current	20/08/2018
CRF - Relapse	CRF	2.0	Current	19/04/2011
CRF - Second Cancer	CRF	2.0	Current	20/04/2015
CRF - Transplant	CRF	2.0	Current	20/04/2015
CRF - Treatment Summary	CRF	4.0	Current	27/11/2015
CRF Completion Guidelines v5	GuidanceDdocument	5	Current	14/03/2018
CRF 'Registration only' Completion Guidelines v2	GuidanceDdocument	2.0	Current	20/08/2018
CTC Contact List	Other	12	Current	05/06/2023
CTCAE	Other	4.03	Current
Drug Supply Guidelines	GuidanceDdocument	4	Current	12/03/2018
File Note: SAE Report v3 not disseminated	Other	N/A	Current	22/01/2016
GDPR Transparency Statement	PatientInformationSheet	1	Current	11/06/2018
GDPR Transparency Statement Tracker	PatientInformationSheet	N/A	Current	24/05/2018
GP Letter v1	GPletter	1.0	Current	11/11/2009
IMP - Destruction log template	Other	1.0	Current	29/11/2010
IMP - Label RA submission form - Nelarabine	Other	N/A	Current	21/10/2010
IMP - Label RA submission form - Oncaspar	Other	N/A	Current	21/10/2010
IMP - Label RA submission form – Palifermin	Other	N/A	Current	21/10/2010
IMP - Label RA submission form - Rituximab	Other	N/A	Current	21/10/2010
IMP - Rituximab Certificate of Clinical Trial Supply	Other	1.0	Current	01/01/2010
IMP - Temperature Monitoring Log Template	Other	1.0	Current	29/11/2010
IMP - UCL CTC Notification of Temperature Excursion Form	Other	2.0	Current	25/02/2014
IMP - UCL CTC Pharmacy Procedure for Reporting Temperature Excursions	Other	1.0	Current	17/09/2010
Incident Report form	Other	3.0	Current	31/07/2018
Insurance 2020-2021	Other	2020-2021	Current	28/07/2020
Laboratory - Sample Request Form	Other	5.0	Current	23/11/2017
MHRA Approval - protocol v12	Amendment	12.0	Current	13/08/2018
Newsletter - Spring 2017	Other	N/A	Current	19/04/2017
Patient Card v1	PatientInformation	1.0	Current	11/11/2009
Patient Information Sheet - Additional Genetic Testing - Bone Marrow	PatientInformationSheet	1.0	Current	09/09/2015
Patient Information Sheet - Additional Genetic Testing - Buccal swab	PatientInformationSheet	1.0	Current	09/09/2015
Patient Information Sheet - Additional PIS Driving and Machines	PatientInformationSheet	1.1	Current	31/08/2017
Patient Information Sheet - Pregnancy Monitoring - Partners	PatientInformationSheet	1.0	Current	01/08/2012
Patient Information Sheet - Pregnancy Monitoring - Patient	PatientInformationSheet	1.0	Current	01/08/2012
Patient Information Sheet v10.0	PatientInformation	10	Current	28/06/2018
Patient Information Sheet/ Consent form - 'Registration Only' Sub-study v3.0	PatientInformationSheet	3.0	Current	28/06/2018
Patient Information Version History	PatientInformationSheet	N/A	Current	28/09/2018
Patient Screening - Informed Consent Log	TrialsLog	1.0	Current	08/12/2011
Patient Screening - Log Instructions	Other	1.0	Current	08/12/2010
Patient Screening - Patient Screening Log	TrialsLog	1.0	Current	08/12/2010
Pregnancy Report	SAEform	3.0	Current	23/11/2017
Pregnancy Report Additional Page	SAEform	1.0	Current	08/12/2010
REC Approval - protocol v12.0	Amendment	12	Current	27/07/2018
Regulatory Guidelines - Declaration of Helsinki	Other	N/A	Current	01/10/2008
Regulatory Guidelines - Principles of ICH GCP	Other	N/A	Current
SAE Form Guidance	GuidanceDdocument	5	Current	04/09/2018
SAE Report	CRF	6	Current	04/09/2018
SAE Report Additional Pages	SAEform	1.0	Current	08/12/2010
SAE Report Fax Header	Other	N/A	Current
Site Information - Investigator Registration Form	Other	1.0	Current	10/08/2011
Site Information - Site Registration Form	Other	1.0	Current	04/07/2011
Site Information - Staff Delegation Log	TrialsLog	1.0	Current	08/08/2011
Study Drug Supplies - Drug Accountability Log Consolidation Oncaspar	Other	2.0	Current	18/05/2015
Study Drug Supplies - Drug Accountability Log Intensification Oncaspar	Other	2.0	Current	18/05/2015
Study Drug Supplies - Drug Accountability Log Palifermin treatment	Other	2.0	Current	18/05/2015
Study Drug Supplies - Drug Accountability Log Phase 1 Oncaspar	Other	2.0	Current	18/05/2015
Study Drug Supplies - Drug Accountability Log Phase 1 Rituximab	Other	2.0	Current	18/05/2015
Study Drug Supplies - Drug Accountability Log Phase 2 Nelarabine	Other	2.0	Current	18/05/2015
Study Drug Supplies - Nelarabine Order Form	Other	1.0	Current	22/10/2010
Study Drug Supplies - Oncaspar order form	Other	4	Current	28/02/2018
Study Drug Supplies - Palifermin Order Form	Other	4	Current	09/09/2015
Study Drug Supplies - Rituximab Order Form	Other	1.0	Current	22/10/2010
Study Drug Supplies - Stock Balance Log Nelarabine	Other	1.0	Current	18/05/2015
Study Drug Supplies - Stock Balance Log Oncaspar	Other	1.0	Current	18/05/2015
Study Drug Supplies - Stock Balance Log Palifermin	Other	1.0	Current	18/05/2015
Study Drug Supplies - Stock Balance Log Rituximab	Other	1.0	Current	18/05/2015
SUSAR Quarterly Line Listings - Apr18-Jun18	Other	N/A	Current
UCL Sponsorship Letter	Other	N/A	Current	25/03/2009
UKALL14 Monitoring Plan	Other	6	Current	01/06/2023
UKALL14 Training Manual - Main study	GuidanceDdocument	1.0	Current	27/11/2017
UKALL14 Training slides - 'Registration only' Sub-study	GuidanceDdocument	1	Current	15/11/2017
Consent Form	InformedConsentForm	1	Historic	11/11/2009
Consent Form	InformedConsentForm	1.1	Historic	03/09/2010
CRF - Annual Follow up	CRF	2.0	Historic	20/04/2015
CRF - Annual Follow up (Relapse/Second Cancer)	CRF	2.0	Historic	20/04/2015
CRF - 'Registration only' Annual Followup	CRF	1.0	Historic	06/12/2017
CRF - 'Registration only' GvHD Form	CRF	1.0	Historic	06/12/2017
CRF - 'Registration only' Induction Treatment	CRF	1.1	Historic	25/01/2018
CRF - 'Registration only' Post-Induction Chemotherapy	CRF	1.1	Historic	25/01/2018
CRF - 'Registration only' Sub-study Entry	CRF	1.0	Historic	24/11/2017
CRF - 'Registration only' Transplant to Day100	CRF	1.0	Historic	06/12/2017
CRF Completion Guidelines	GuidanceDdocument	4.0	Historic	10/03/2016
CRF 'Registration only' Induction Treatment form	CRF	1	Historic	18/01/2018
CRF 'Registration only' Post-Induction Chemotherapy form	CRF	1	Historic	18/01/2018
CRF 'Registration-only' Completion Guidelines	GuidanceDdocument	1.1	Historic	20/03/2018
CTC contact list	Other	8	Historic	11/02/2019
CTC contact list	Other	9	Historic	06/03/2019
CTC contact list	Other	10	Historic	09/12/2019
CTC contact list	Other	7.0	Historic	29/08/2018
CTC Contact list	Other	6.0	Historic	08/02/2017
HRA Approval - protocol v12	Amendment	12.0	Historic	10/09/2018
Incident Report form	Other	2.0	Historic	25/06/2015
Insurance 2009-2010	Other	2009-2010	Historic
Insurance 2010-2011	Other	2010-2011	Historic
Insurance 2011-2012	Other	2011-2012	Historic
Insurance 2012-2013	Other	2012-2013	Historic
Insurance 2013-2014	Other	2013-2014	Historic
Insurance 2014-2015	Other	2014-2015	Historic
Insurance 2015-2016	Other	2015-2016	Historic
Insurance 2016- 2017	Other	2016-2017	Historic
Insurance 2017-2018	Other	2017-2018	Historic
Insurance 2018-2019	Other	2018-2019	Historic
Insurance 2019-2020	Other	2019-2020	Historic
Insurance UCL Letter	Other	N/A	Historic	15/05/2009
ISF - Site Quality Control Checklist	Other	9.0	Historic	30/03/2017
ISF - Site Quality Control Checklist	Other	14	Historic	20/09/2018
Laboratory - Price List UCL Adult ALL Lab	Other	N/A	Historic	08/08/2010
Laboratory - Sample Request Form	Other	3.0	Historic	09/11/2015
MHRA Approval - Labelling	Amendment	N/A	Historic	03/11/2010
MHRA Approval - PIS v2	Amendment	N/A	Historic	23/02/2010
MHRA Approval - protocol v11	Amendment	11	Historic	21/11/2017
MHRA Approval - Protocol v2	Amendment	N/A	Historic	21/06/2010
MHRA Approval - Protocol v3	Amendment	N/A	Historic	17/09/2010
MHRA Approval - Protocol v4	Amendment	N/A	Historic	09/05/2012
MHRA Approval - Protocol v5	Amendment	N/A	Historic	27/09/2012
MHRA Approval - Protocol v6	Amendment	N/A	Historic	15/07/2014
MHRA Approval - Protocol v6.1	Amendment	N/A	Historic	11/03/2015
MHRA Approval - Protocol v7	Amendment	N/A	Historic	15/11/2015
MHRA Approval - Protocol v8	Amendment	N/A	Historic	15/06/2016
MHRA Approval - Protocol v9	Amendment	N/A	Historic	13/03/2017
MHRA Initial Approval	Other	N/A	Historic	13/01/2010
MHRA Urgent Safety Measure correspondence	Other	N/A	Historic	23/04/2012
Monitoring Plan	Other	4.0	Historic	18/10/2016
Newsletter - Christmas 2011	Other	N/A	Historic	01/12/2011
Newsletter - Christmas 2012	Other	N/A	Historic	01/12/2012
Newsletter - Christmas 2013	Other	N/A	Historic	01/12/2013
Newsletter - Christmas 2014	Other	N/A	Historic	01/12/2014
Newsletter - Christmas 2015	Other	N/A	Historic	01/12/2015
Newsletter - Christmas 2019	Other	N/A	Historic
Newsletter - Easter 2011	Other	N/A	Historic	01/03/2011
Newsletter - Easter 2012	Other	N/A	Historic	01/03/2012
Newsletter - Easter 2013	Other	N/A	Historic	01/03/2013
Newsletter - January 2019	Other	N/A	Historic
Newsletter - May 2015	Other	N/A	Historic	01/05/2015
Newsletter - MRD lab move	Other	N/A	Historic	15/05/2015
Newsletter - Summer 2018	Other	N/A	Historic
Patient Information Sheet	PatientInformationSheet	7.0	Historic	17/02/2017
Patient Information Sheet - Additional Suspension of Palifermin	Other	1	Historic	13/04/2016
Patient Information Sheet v2	PatientInformationSheet	2.0	Historic	24/12/2009
Patient Information Sheet v2.1	PatientInformationSheet	2.1	Historic	17/05/2010
Patient Information Sheet v3	PatientInformationSheet	3.0	Historic	18/08/2010
Patient Information Sheet v4	PatientInformationSheet	4.0	Historic	01/08/2012
Patient Information Sheet v4.1	PatientInformationSheet	4.1	Historic	16/05/2013
Patient Information Sheet v5	PatientInformationSheet	5.0	Historic	13/03/2014
Patient Information Sheet v5.1	PatientInformationSheet	5.1	Historic	16/06/2014
Patient Information Sheet v5.2	PatientInformationSheet	5.2	Historic	29/04/2015
Patient Information Sheet v5.3	PatientInformationSheet	5.3	Historic	09/09/2015
Patient Information Sheet v6	PatientInformationSheet	6.0	Historic	12/05/2016
Patient Information Sheet v8	PatientInformationSheet	8.0	Historic	09/08/2017
Patient Information Sheet v9	PatientInformationSheet	9.0	Historic	11/09/2017
Patient Information Sheet/Consent form - 'Registration only' sub-study v2.0	PatientInformationSheet	2.0	Historic	11/09/2017
Patient Log	Other	1	Historic	08/12/2010
Pregnancy Report	SAEform	2.0	Historic	21/01/2016
PSF - Site Quality Control Checklist	Other	8.0	Historic	30/03/2017
PSF - Site Quality Control Checklist	Other	12.0	Historic	20/09/2018
REC Approval - Consent period	Amendment	N/A	Historic	24/08/2011
REC Approval - PIS v4.1	Amendment	N/A	Historic	17/05/2013
REC Approval - PIS v5	Amendment	N/A	Historic	02/04/2014
REC Approval - PIS v5.2	Amendment	N/A	Historic	21/05/2015
REC Approval - PIS v8	Amendment	N/A	Historic	05/09/2017
REC Approval - protocol v11.0	Amendment	11	Historic	30/10/2017
REC Approval - Protocol v2	Amendment	N/A	Historic	07/06/2010
REC Approval - Protocol v3	Amendment	N/A	Historic	08/09/2010
REC Approval - Protocol v4	Amendment	N/A	Historic	16/05/2012
REC Approval - Protocol v5	Amendment	N/A	Historic	23/08/2012
REC Approval - Protocol v6	Amendment	N/A	Historic	09/07/2014
REC Approval - Protocol v6.1	Amendment	N/A	Historic	23/02/2015
REC Approval - Protocol v7	Amendment	N/A	Historic	30/09/2015
REC Approval - Protocol v8	Amendment	N/A	Historic	06/06/2016
REC Approval - Protocol v9	Amendment	N/A	Historic	09/03/2017
REC Initial Approval	Other	N/A	Historic	13/01/2010
'Registration-only' CRF Completion Guidelines	GuidanceDdocument	1	Historic	14/03/2018
Rejection of Protocol v10 amendment correspondence	Other	12/07/2017	Historic	12/07/2017
SAE Form Guidance	GuidanceDdocument	4.0	Historic	23/11/2017
SAE Form Guidance	GuidanceDdocument	3.0	Historic	10/02/2017
SAE Report	SAEform	4.0	Historic	21/01/2016
SAE Report	Other	5.0	Historic	23/11/2017
SPC - Atriance	Other	30/10/2020	Historic	30/10/2020
SPC - Atriance	Other	N/A	Historic	01/04/2015
SPC - Kepivance	Other	N/A	Historic	01/05/2013
SPC - Kepivance	Other	08/03/2016	Historic	08/03/2016
SPC - Oncaspar	Other	Nov 2020	Historic	01/11/2020
SPC - Oncaspar	Other	N/A	Historic	01/06/2014
SPC - Rituximab	Other	27/02/2020	Historic	27/02/2020
Study Drug Supplies - Drug Supply Guidelines	Other	3.0	Historic	23/11/2017
Study Drug Supplies - Drug Supply Guidelines	Other	2.1	Historic	25/02/2014
Study Drug Supplies - Oncaspar Order Form	Other	3.0	Historic	11/02/2013
SUSAR Quarterly Line Listing - 01Apr20 - 30Jun20	Other	N/A	Historic	30/06/2020
SUSAR Quarterly Line Listing - 01Apr21 - 30Jun21	Other	N/A	Historic
SUSAR Quarterly Line Listing - 01Jan20 - 31Mar20	Other	NA	Historic	31/03/2020
SUSAR Quarterly Line Listing - 01Jan21 - 31Mar21	Other	N/A	Historic	31/03/2021
SUSAR Quarterly Line Listing - 01Jul18-30Sep18	Other	N/A	Historic
SUSAR Quarterly Line Listing - 01Jul20 - 30Sep20	Other	N/A	Historic	30/09/2020
SUSAR Quarterly Line Listing - 01Oct20 - 31Dec20	Other	N/A	Historic	31/12/2020
SUSAR Quarterly Line Listings - 01Apr19-30Jun19	Other	n/a	Historic
SUSAR Quarterly Line Listings - 01Jan2019-31Mar2019	Other	n/a	Historic
SUSAR Quarterly Line Listings - 01Jul19-30Sep19	Other	n/a	Historic
SUSAR Quarterly Line Listings - 01Oct18-31Dec18	Other	n/a	Historic
SUSAR Quarterly Line Listings - 01Oct19-31Dec19	Other	n/a	Historic
SUSAR Quarterly Line Listings - Apr15-Jun15	Other	N/A	Historic
SUSAR Quarterly Line Listings - Apr16-Jun16	Other	N/A	Historic
SUSAR Quarterly Line Listings - Apr17-Jun17	Other	N/A	Historic
SUSAR Quarterly Line Listings - Aug12	Other	N/A	Historic
SUSAR Quarterly Line Listings - Jan15-Mar15	Other	N/A	Historic
SUSAR Quarterly Line Listings - Jan16-Mar16	Other	N/A	Historic
SUSAR Quarterly Line Listings - Jan17-Mar17	Other	N/A	Historic
SUSAR Quarterly Line Listings - Jan18-Mar18	Other	N/A	Historic
SUSAR Quarterly Line Listings - Jul15-Sep15	Other	N/A	Historic
SUSAR Quarterly Line Listings - Jul16-Sep16	Other	N/A	Historic
SUSAR Quarterly Line Listings - Jul17-Sep17	Other	N/A	Historic
SUSAR Quarterly Line Listings - Jun14-Sept14	Other	N/A	Historic
SUSAR Quarterly Line Listings - Oct15-Dec15	Other	N/A	Historic
SUSAR Quarterly Line Listings - Oct16-Dec16	Other	N/A	Historic
SUSAR Quarterly Line Listings - Oct17-Dec17	Other	N/A	Historic
SUSAR Quarterly Line Listings - Sept14-Dec14	Other	N/A	Historic
UKALL14 - Patient Information Sheet v7.0 17.02.2017_20022020_0.doc	PatientInformationSheet	7	Historic	17/02/2017
UKALL14 Prescriptions - Memorandum to Investigators and Pharmacists	Other	N/A	Historic	26/01/2016
Urgent Safety Measure Correspondence	Other	24/04/2012	Historic	24/04/2012

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Email:
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Telephone:
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Fax:
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