The CTC offices are currently closed for refurbishment. Access to trial TMFs and patient records will be limited during this period. We will still be able to receive post during this time, but there may be a small delay in responding to this. Our fax lines may also be subject to disruption. Where possible, please direct all correspondence via email to trial-specific email addresses. We appreciate your patience and understanding.

Due to COVID-19 and current government guidance, UCL CTC staff continue to work remotely with limited access to the office. Please continue to email the trial specific mailbox with any urgent queries. For paper CRF trials, please continue to copy and scan CRFs to the trial inboxes (remove all patient identifiers except Trial Number and Initials) until further notice.

Trial Details
Trial status:
Active (recruiting)
Recruitment start date:
BCRT: the Bone Cancer Research Trust
Chief Investigator:
Dr Sandra Strauss
Recruitment target:
at least 160
EudraCT number:
Contact details:
Lay summary:
Improving outcomes through Collaboration in OsteosarComa
Design: Prospective observational cohort study.

No treatments are specified in ICONIC. Patients should be treated according to national guidelines including UK guidelines for the management of bone sarcomas and applicable current and future NICE guidance. 

Duration of recruitment: No treatment is prescribed for this trial, but patients will be followed up for up to four years after registration.
To improve treatment and outcomes for patients with osteosarcoma (OS) by establishing a clinically annotated cohort of newly diagnosed patients with OS with longitudinal collection of biospecimens.
Trial protocols
Trial protocols must not be applied to patients treated outside trials. UCL CTC can only ensure that approved trial investigators are provided with amendments to protocols.
NameVersionCurrent versRelease dateDownload
ICONICProtocol_v2_23_01_2020_unsigned_25062020_0.pdf2 Current 23/02/2020
Trial documents
No documents have been currently made available for download
Contact Us
Cancer Research UK & UCL Cancer Trials Centre
University College London
90 Tottenham Court Road

View map
+44 (0)20 7679 9898 (General CTC Enquiries)
020 7679 9899
University College London, Gower Street, London, WC1E 6BT +44 (0)20 7679 2000

Copyright © 2021 UCL | Disclaimer | Freedom of Information | Accessibility | Privacy | Cookies | Contact Us