The CTC offices are currently closed for refurbishment. Access to trial TMFs and patient records will be limited during this period. We will still be able to receive post during this time, but there may be a small delay in responding to this. Our fax lines may also be subject to disruption. Where possible, please direct all correspondence via email to trial-specific email addresses. We appreciate your patience and understanding.

Due to COVID-19 and current government guidance, UCL CTC staff continue to work remotely with limited access to the office. Please continue to email the trial specific mailbox with any urgent queries. For paper CRF trials, please continue to copy and scan CRFs to the trial inboxes (remove all patient identifiers except Trial Number and Initials) until further notice.

 
Recruitment underway for ovarian cancer study
13 January 2020
The first two patients have been registered to a recently opened gynaecological cancer trial run by the CR UK & UCL Cancer Trials Centre. 

PROMPT is a phase 2 study for patients with recurrent ovarian, fallopian tube or peritoneal cancer. The trial will investigate the role of an immunotherapy drug called pembrolizumab following previous weekly paclitaxel treatment for those who enter. Opened across 3 sites, the study aims to see if pembrolizumab can increase the time a patient lives with ovarian cancer without the disease getting worse. PROMPT aims to recruit 28 patients in total. 

Tami Grunewald, Clinical Research Fellow for PROMPT, explained in more detail:

‘Women with platinum resistant ovarian cancer have very limited treatment options, with very few patients responding to standard chemotherapy. This study is aimed at attempting to prolong the response to conventional treatment using maintenance immunotherapy. 

'Immune checkpoint inhibitors have now become the standard of care in a number of different solid tumours, but their role in ovarian cancer remains unclear. The exploratory element of this study will hopefully provide some insight into the ovarian tumour immune microenvironment, with the potential of identifying those patients who will benefit from immunotherapy’. 

PROMPT would like to thank all the hospital teams involved in the set up and running of the study. PROMPT has funding support from Merck Sharp & Dohme Ltd.
 
Recruitment will continue until November 2020. Keep an eye on the CTC website for more details.
Contact Us
Cancer Research UK & UCL Cancer Trials Centre
University College London
90 Tottenham Court Road
London
W1T 4TJ

View map
Email:
ctc.enquiries@ucl.ac.uk
Telephone:
+44 (0)20 7679 9898 (General CTC Enquiries)
Fax:
020 7679 9899
University College London, Gower Street, London, WC1E 6BT +44 (0)20 7679 2000

Copyright © 2021 UCL | Disclaimer | Freedom of Information | Accessibility | Privacy | Cookies | Contact Us