Due to COVID-19 and current government guidance, UCL CTC staff continue to work remotely however we are beginning to have limited access to the office from 6th July 2020. Please continue to email the trial specific mailbox with any urgent queries. For paper CRF trials, please continue to copy and scan CRFs to the trial inboxes (remove all patient identifiers except Trial Number and Initials) until further notice.

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Trials portfolio

ABC-07
Addition of stereotactic body radiotherapy to systemic chemotherapy in locally advanced biliary tract cancers

ABC-07 is a multicentre phase II trial, with a 2:1 randomisation between 6 cycles of cisplatin and gemcitabine (CisGem) chemotherapy followed by Stereotactic Body Radiotherapy (SBRT), and 8 cycles Cis [...]

Area: Upper gastro-intestinal cancer

Phase: Phase II

Status: Active (recruiting)

ABC-11
A seamless phase Ib/II study of selective HDAC6 inhibition with KA2507 in advanced biliary tract cancer previously treated with standard of care chemotherapy

Area: Upper gastro-intestinal cancer

Phase: Phase I/II

Status: In set-up (funded)

BTC VTB
Biliary Tract Cancer Virtual Tissue Bank

A series of advanced biliary tract cancer (ABC) trials plan to investigate the value of interventions in addition to CisGem. This portfolio of trials include ABC-02,ABC-03, ABC-06, ABC-07, ACTICCA-1, [...]

Area: Upper gastro-intestinal cancer

Phase: Tissue collection

Status: In follow-up (non-recruiting)

VEROnA
A pilot, open label, single-arm, phase 0, window of opportunity study of vandetanib-eluting radiopaque embolic beads (BTG-002814) in patients with resectable liver malignancies

VEROnA is a pilot, open label, single arm, Phase 0 window of opportunity study of vandetanib eluting radiopaque embolic beads.

Area: Upper gastro-intestinal cancer

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