The CTC offices are currently closed for refurbishment. Access to trial TMFs and patient records will be limited during this period. We will still be able to receive post during this time, but there may be a small delay in responding to this. Our fax lines may also be subject to disruption. Where possible, please direct all correspondence via email to trial-specific email addresses. We appreciate your patience and understanding.

Due to COVID-19 and current government guidance, UCL CTC staff continue to work remotely with limited access to the office. Please continue to email the trial specific mailbox with any urgent queries. For paper CRF trials, please continue to copy and scan CRFs to the trial inboxes (remove all patient identifiers except Trial Number and Initials) until further notice.

 
PROMPT underway at London hospitals
22 May 2019
A CTC study investigating the treatment of recurrent ovarian cancer has opened to recruitment at UCLH and Hammersmith Hospital. 

PROMPT is a phase II trial which will give an immunotherapy drug to patients who have previously received chemotherapy for an ovarian tumour. The drug, which is called pembrolizumab, works by stimulating the body’s immune system to fight cancer cells. Researchers are looking to find out whether this treatment can help prevent the return or growth of a patient’s tumour.  

The study also involves two biopsies for the patients who participate, the first taken after a patient is recruited, and the next taken before their fourth dose of immunotherapy treatment. The biopsies are intended to help researchers better understand the effects pembrolizumab has on the immune system. Analysing these samples will also create data which might provide further help in selecting suitable candidates for treatment in the future.

Trial coordinator Anne-Marie Mullin was happy to see the first sites on board: ‘This is a very promising study, and it’s great to have both hospitals taking part in a trial which could have such an influence on the future treatment of ovarian cancer’.

PROMPT is now recruiting patients and will soon be open to a further hospital in London. It is supported by Merck Sharp & Dohme Ltd.  
Contact Us
Cancer Research UK & UCL Cancer Trials Centre
University College London
90 Tottenham Court Road
London
W1T 4TJ

View map
Email:
ctc.enquiries@ucl.ac.uk
Telephone:
+44 (0)20 7679 9898 (General CTC Enquiries)
Fax:
020 7679 9899
University College London, Gower Street, London, WC1E 6BT +44 (0)20 7679 2000

Copyright © 2021 UCL | Disclaimer | Freedom of Information | Accessibility | Privacy | Cookies | Contact Us