Advanced
Trials portfolio
ARISTOTLE
A phase III trial comparing standard versus novel CRT as pre-operative treatment for MRI defined locally advanced rectal cancer
ARISTOTLE is a multicentre, phase III, randomised trial comparing standard neoadjuvant chemoradiotherapy (CRT) of oral capecitabine and radiotherapy versus standard CRT with the addition of irinotecan [...]
Area: Lower gastro-intestinal cancer
Phase: Phase III
Status: In follow-up (non-recruiting)
BACCHUS
A phase II Multicentre Open-label Randomised Study of Neoadjuvant Chemotherapy and Bevacizumab in Patients with MRI defined High-Risk Cancer of the Rectum
A Phase II, Multicentre, Open-label, Randomised Study of Neoadjuvant Chemotherapy and Bevacizumab in Patients with MRI defined High-Risk Cancer of the Rectum.
Area: Lower gastro-intestinal cancer
Phase: Phase II
Status:
EXCITE
Erbitux, Xeloda, Campto, Irradiation Then Excision for locally advanced rectal cancer (North West/North Wales Clinical Oncology Group-04 on behalf of the NCRI rectal cancer subgroup)
Area: Lower gastro-intestinal cancer
Phase: Phase II
Status:
NEOPRISM-CRC
NEOadjuvant PembRolizumab In Stratified Medicine – ColoRectalCancer
The NEOPRISM-CRC study is a phase II clinical trial. The purpose of the trial is to evaluate the efficacy and safety of pembrolizumab (Study IMP) in patients with high risk Stage 2 or Stage 3 MMR-defi [...]
Area: Lower gastro-intestinal cancer
Phase: Phase II
Status: Active (recruiting)
PANTHER
AZD8931, an EGFR inhibitor, in combination with FOLFIRI: A Phase I/II study to determine the importance of schedule and activity in colorectal cancer
PANTHER is a phase I/II trial in patients with recurrent or metastatic colorectal cancer. Phase I has closed to recruitment. The phase II part of the study is a single arm trial of AZD8931 + FOLFIRI.
Area: Lower gastro-intestinal cancer
Phase: Phase I/II
Status: Closed
Streamline-C
Streamlining staging of colorectal cancer with Whole Body MRI
Multicentre comparison
Area: Lower gastro-intestinal cancer
Phase: Observational trials
Status: Closed
Streamline-L
Streamlining staging of lung cancer with Whole Body MRI
Multicentre comparison
Area: Lower gastro-intestinal cancer
Phase: Observational trials
Status: Closed
Contact Us
Cancer Research UK & UCL Cancer Trials Centre
University College London
90 Tottenham Court Road
London
W1T 4TJ

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Email:
ctc.enquiries@ucl.ac.uk
Telephone:
+44 (0)20 7679 9898 (General CTC Enquiries)
Fax:
020 7679 9899
University College London, Gower Street, London, WC1E 6BT +44 (0)20 7679 2000

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