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Trials portfolio
GALA-5 Long Term Follow Up
Long term follow up of patients in the GALA5 trial: an Evaluation of the Tolerability and Feasibility of combining 5-Amino-Levulinic Acid (5ALA) with Carmustine Wafers (Gliadel) in the Surgical Management of Primary Glioblastoma
The GALA-5 trial was a single arm feasibility study to evaluate the safety and tolerability of combining 2 technologies (5-ALA and Carmustine wafers) in the surgical management of patients with gliobl [...]
Area: Brain cancer
Phase: Observational trials
Status: In follow-up (non-recruiting)
HCQ
A randomised phase 2 trial investigating the additional benefit of hydroxychloroquine (HCQ) to short course radiotherapy (SCRT) in patients aged 70 years and older with high grade gliomas (HGG)
HCQ is a randomised (2:1), multicentre, phase II study comparing hydroxychloroquine (HCQ) and short course radiotherapy (SCRT) with SCRT alone to examine the effect on one-year survival in patients ag [...]
Area: Brain cancer
Phase: Phase II
Status: In follow-up (non-recruiting)
HIPPO
A randomized phase II trial of Hippocampal Sparing versus Conventional Whole Brain Radiotherapy after surgical resection or radiosurgery in favourable prognosis patients with 1-4 brain metastases
HIPPO is a 1:1 randomised multicentre phase II study investigating Hippocampal Sparing Whole Brain Radiotherapy (HS-WBRT) versus standard Whole Brain Radiotherapy (WBRT) after neurosurgery or stereota [...]
Area: Brain cancer
Phase: Phase II
Status: In follow-up (non-recruiting)
NeAT Glio
A Phase II Trial of Neoadjuvant Therapy in Patients with Newly Diagnosed Glioblastoma
Single arm single stage phase II trial to evaulate whether the addition of ipilimumab prior to current standard of care of surgery and chemoradiotherapy will improve survival in patients with newly di [...]
Area: Brain cancer
Phase: Phase II
Status: In set-up (funded)
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