Due to COVID-19 and current government guidance, UCL CTC staff continue to work remotely however we are beginning to have limited access to the office from 6th July 2020. Please continue to email the trial specific mailbox with any urgent queries. For paper CRF trials, please continue to copy and scan CRFs to the trial inboxes (remove all patient identifiers except Trial Number and Initials) until further notice.

 
Advanced
Trials portfolio
ICON9
An international phase III randomised study to evaluate the efficacy of maintenance therapy with olaparib and cediranib or olaparib alone in patients with relapsed platinum-sensitive ovarian cancer following a response to platinum-based chemotherapy
ICON9 is an international phase III randomised study to evaluate the efficacy of maintenance olaparib and cediranib combination therapy or olaparib alone in patients with relapsed platinum-sensitive o [...]
Area: Gynaecological cancer
Phase: Phase III
Status: Active (recruiting)
INTERLACE
A phase III multicentre trial of weekly induction chemotherapy followed by standard chemoradiation vs standard chemoradioation alone in patients with locally advanced cervical cancer
INTERLACE is a phase III multicentre trial of weekly induction chemotherapy followed by standard chemoradiation versus standard chemoradiation alone in patients with locally advanced cervical cancer.
Area: Gynaecological cancer
Phase: Phase III
Status: Active (recruiting)
METRO-BIBF
Phase II, randomised, placebo controlled, multicentre, feasibility study of low dose (metronomic) cyclophosphamide with or without nintedanib (BIBF1120) in advanced ovarian cancer (METRO–BIBF)
METRO-BIBF is a phase II, randomised, placebo-controlled, multi-centre, feasibility study of low dose (metronomic) cyclophosphamide with and without nintedanib (BIBF 1120) in advanced ovarian cancer.
Area: Gynaecological cancer
Phase: Phase II
Status: Closed
PEACOCC
A phase II study of pembrolizumab in patients with advanced gynaecological clear cell cancer
PEACOCC is a phase II, single Arm, UK multi-centre study. All patients will receive the same dose of Pembrolizumab. All eligible patients will have advanced gynecological clear cell cancer. PEACOCC is [...]
Area: Gynaecological cancer
Phase: Phase II
Status: Active (recruiting)
PETROC
A Phase II/III study of intraperitoneal (IP) plus intravenous (IV) chemotherapy versus IV carboplatin plus paclitaxel in patients with epithelial ovarian cancer optimally debulked at surgery following neoadjuvant intravenous chemotherapy (PETROC/OV21)
This is an international randomised, non-blinded multicentre phase II Gynecologic Cancer Intergroup trial coordinated by the NCIC Clinical Trials Group in conjunction with SWOG (US), the Cancer Resear [...]
Area: Gynaecological cancer
Phase: Phase II
Status: Closed
PORTEC-3
Randomized Phase III Trial Comparing Concurrent Chemoradiation and Adjuvant Chemotherapy with Pelvic Radiation Alone in High Risk and Advanced Stage Endometrial Carcinoma
PORTEC-3 is a prospective, multicentre, randomised Phase III intergroup trial led by the Dutch Cooperative Gynaecologic Oncology Group, in collaboration with the UK National Cancer Research Institute, [...]
Area: Gynaecological cancer
Phase: Phase III
Status: In follow-up (non-recruiting)
PROMPT
A phase II study of maintenance pembrolizumab following weekly paclitaxel for recurrent ovarian, fallopian tube or peritoneal cancer
PROMPT is a phase II single-arm, UK multi-centre study. All patients will receive the same dose of Pembrolizumab. All eligible patients will have recurrent ovarian, fallopian tube or peritoneal cancer [...]
Area: Gynaecological cancer
Phase: Phase II
Status: Active (recruiting)
SHAPE
A randomised phase III trial comparing radical hysterectomy and pelvic node dissection vs simple hysterectomy and pelvic node dissection in patients with low-risk early-stage cervical cancer
SHAPE is a multi-centre, international, prospective, randomised phase III trial of radical hysterectomy and pelvic node dissection versus simple hysterectomy and pelvic node dissection in patients wit [...]
Area: Gynaecological cancer
Phase: Phase III
Status: In follow-up (non-recruiting)
STATEC
A randomised trial of non-Selective versus selective adjuvant Therapy in high risk Apparent sTage 1 Endometrial Cancer
STATEC is a randomised (1:1) multicentre international phase III trial of hysterectomy with lymphadenectomy vs hysterectomy alone in women with high risk apparent stage I endometrial cancer.
Area: Gynaecological cancer
Phase: Phase III
Status: Recruitment suspended
TRIOC
A phase II study to assess the activity of TroVax (MVA-5T4) versus placebo in patients with relapsed asymptomatic epithelial ovarian, fallopian tube or primary peritoneal cancer
TRIOC is a prospective multicentre phase II trial in patients with epithelial ovarian, fallopian tube or primary peritoneal cancer who develop asymptomatic relapse as confirmed by either elevated CA-1 [...]
Area: Gynaecological cancer
Phase: Phase II
Status: Closed
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London
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Email:
ctc.enquiries@ucl.ac.uk
Telephone:
+44 (0)20 7679 9898 (General CTC Enquiries)
Fax:
020 7679 9899
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